Alveolar Macrophage ABCG1 Deficiency Promotes Pulmonary Granulomatous Inflammation
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چکیده
منابع مشابه
SOCS3 deficiency promotes M1 macrophage polarization and inflammation.
Macrophages participate in both the amplification of inflammation at the time of injury and downregulation of the inflammatory response to avoid excess tissue damage. These divergent functions of macrophages are dictated by their microenvironment, especially cytokines, which promote a spectrum of macrophage phenotypes. The M1 proinflammatory phenotype is induced by LPS, IFN-γ, and GM-CSF, and I...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2019
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2018-0365oc